James S. Pankow, Ph.D., M.P.H.

Selected Publications:

Wassel CL, Pankow JS, Rasmussen-Torvik LJ, Li N, Taylor KD, Guo X, Goodarzi MO, Palmas W, Post W. Association of SNPs in ADIPOQ with subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis (MESA). Obesity 2011; 19: 840-847. PMCID: PMC Journal – In Process

Djoussé L, Hopkins PN, North KE, Pankow JS, Arnett DK, Ellison RC. Chocolate consumption is inversely associated with prevalent coronary heart disease: the National Heart, Lung, and Blood Institute Family Heart Study. Clinical Nutrition 2011;30: 182-187. PMCID: PMC3039704

Rasmussen-Torvik LJ, Li M, Kao W, Couper D, Boerwinkle E, Bielinski SJ, Folsom AR, Pankow JS. Association of a fasting glucose genetic risk score with subclinical atherosclerosis:  The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes 2011; 60: 331-335. PMCID: PMC3012190

Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J.  Links between insulin resistance, adenosine A2B receptors and inflammatory markers in mice and humans.  Diabetes  2011; 60:6 69-679. PMCID: PMC3028369

DehghanA, DupuisJ, Barbalic M, BisJ, EiriksdottirG, ... Pankow JS, et al. Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple Loci for C-reactive protein levels. Circulation 2011;123:731-738. PMCID: PMC3147232

Kraja AT, Vaidya D, Pankow JS, Goodarzi MO, Assimes TL, et al. A bivariate genome-wide approach to metabolic syndrome: STAMPEED Consortium. Diabetes 2011; 60: 1329-1339. PMCID: PMC3064107

Chatterjee R, Yeh HC, Shafi T, Anderson C, Pankow JS, Miller ER, Levine D, Selvin E, Brancati F. Serum potassium and the black-white disparity in diabetes risk: The Atherosclerosis Risk in Communities Study. American Journal of Clinical Nutrition 2011; 1087-1091. PMCID: PMC3076658

Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, ... Pankow JS, et al. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height. American Journal of Human Genetics 2011; 88: 6-18. PMCID: PMC3014369

Basu S, Pankow JS. An alternative model for quantitative trait loci (QTL) analysis in general pedigrees. American Journal of Human Genetics 2011; 75: 292-304. PMCID: PMC Journal – In Process

Nash SD, Cruickshanks KJ, Klein R, Klein BEK, Archer CW, Nieto FJ, Huang GH, Pankow JS, Miller MB, Tweed TS, Baldwin CT. The prevalence of hearing impairment and associated risk factors. The Beaver Dam Offspring Study. Archives of Otolaryngology Head and Neck Surgery 2011;137:432-439. PMCID: PMC3096733

Bielinski SJ, Hall JL, Pankow JS, Boerwinkle E, Matijevic-Aleksic N, He M, Folsom AR. Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: The Atherosclerosis Risk in Communities (ARIC) MRI study. Human Genetics 2011;129:655-662. PMCID: PMC Journal – In Process

Demerath EW, Lutsey PL, Monda KL, Kao WH, Bressler J, Pankow JS, North KE, Folsom AR. Interaction of FTO and physical activity level on adiposity in African American and European-American adults: The ARIC Study. Obesity 2011:19:1866-1872. PMCID: PMC Journal – In Process

Kanoni S, Nettleton J, Hivert MF, Ye Z, van Rooij F, ... Pankow J, et al. Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes 2011;60:2407-2416 PMCID: PMC3161318

Maruthur NM, Kao WHL, Clark J, Brancati F, Cheng CY, Pankow JS, Selvin E. Does genetic ancestry explain higher values of glycated hemoglobin in African Americans? Diabetes 2011;60:2434-2438. PMCID: PMC3161314

Bielinski SJ, Pankow JS, Rasmussen-Torvik LJ, Bailey K, Li M, Selvin E, Couper D, Vazquez G, Brancati F. Strength of association for incident diabetes risk factors according diabetes case definitions: The Atherosclerosis Risk in Communities (ARIC) Study. American Journal of Epidemiology 2012; 175: 466-472. PMCID: PMC Journal – In Process

Manichaikul A, Chen WM, Williams K, Wong Q, Sale MM, Pankow JS, Tsai MY, Rotter JI, Rich SS, Mychaleckyj JC. Analysis of family- and population-based samples in cohort genome-wide association studies. Human Genetics 2012;131:275-287. PMCID: PMC Journal – In Process

Irvin MR, Wineinger N, Rice TK, Pajewski NM, Kabagambe EK, Gu CC, Pankow J, North KE^, Wilk JB, Freedman BI, Franceschini N, Broeckel U, Tiwari HK, Arnett DK.. Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN Study. PLoS ONE 2011;6:e24052. PMCID: PMC3162025

Zhan W, Cruickshanks KJ, Klein BE, Klein R, Huang GH, Pankow JS, Gangnon RE, Tweed TS. Modifiable Determinants of Hearing Impairment in Adults. Prevention Medicine 2011;53:338-342PMCID: PMC3208793

Huxley RR, Alonso A, Lopez FL, Filion KB, Agarwal SK, Loehr LR, Soliman EZ, Pankow JS, Selvin E.  Diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities Study.  Heart 2012;98:133-138. PMCID: PMC3237721

Rahilly-Tierney CR, Arnett DK, North KE, Pankow JS, Hunt SC, Ellison RC, Gaziano JM, Djousse L. Apolipoprotein epsilon-4 polymorphism does not modify the association between body mass index and high-density lipoprotein cholesterol: a cross-sectional cohort study. Lipids in Health and Disease 2011;10:167. PMCID: PMC3187732

Zhong W, Cruickshanks KJ, Huang GH, Klein BE, Klein R, Nieto FJ, Pankow JS, Schubert CR. Carotid atherosclerosis and cognitive function in midlife: The Beaver Dam Offspring Study. Atherosclerosis 2011;219:330-333. PMCID: PMC3206159

Avery CL, He Q, North KE, Ambite JL, Boerwinkle E, Fornage M, Hindorff LA, Kooperbert C, Meigs JB, Pankow JS, Pendergrass SA, Psaty BM, Ritchie MD, Rotter JI, Taylor KD, Wilkens LR, Heiss G, Lin DY. A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genetics 2011;7:e1002322. PMCID: PMC3192835

Lutsey PL, Rasmussen-Torvik LJ, Pankow JS, Alonso A, Smolenski  DJ, Tang W, Coresh J, Volcik KA, Ballantyne CM, Boerwinkle E, Folsom AR. Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among Caucasians: The Atherosclerosis Risk in Communities (ARIC) study. Circulation Cardiovascular Genetics 2012;5:73-80. PMCID: PMC Journal – In Process

Walford GA, Green T, Neale B, Isakova T, Grant SFA, Fox CS, Pankow JS, Wilson JG, Meigs JB, Siscovick DS, Bowden DW, Daly MJ, Florez JC. Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism. Diabetologia 2012;55:331-339

Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, ... Pankow JS, et al. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics 2012; 9: 410-425. PMCID: PMC3309185

Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, ... Pankow JS, et al.  Novel Loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.  PLoS Genetics 2012; 8:e1002607. PMCID: PMC – Journal in Process

Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, ... Pankow JS, et al. A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012; 7:e29202.  PMCID: PMC – Journal in Process

Schubert CR, Cruickshanks KJ, Fischer ME, Huang GH, Klein BE, Klein R, Pankow JS, Nondahl DM. Olfactory impairment in an adult population: The Beaver Dam Offspring Study. Chemical Senses 2012; 37: 325-334.  PMCID: PMC3325763

Rasmussen-Torvik L, Pankow JS et al. Fasting glucose GWAS candidate region analysis across ethnic groups in the Multi-Ethnic study of Atherosclerosis (MESA). In press, Genetic Epidemiology. PMCID: PMC – Journal in Process

Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, ... Pankow JS, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics 2012; 44: 659-669. PMCID: PMC – Journal in Process

Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, ... Pankow JS, et al. No interactions between previously associated 2-h glucose gene variants and physical activity or BMI on 2-h glucose levels. Diabetes 2012; 61; 1291-1296. PMCID: PMC3331745

Schneider AL, Pankow JS, Heiss G, Selvin E. Validity and reliability of self-reported diabetes in the Atherosclerosis Risk in Communities (ARIC) Study. In press, American Journal of Epidemiology. PMCID: PMC – Journal in Process

Setodji CM, Scheuner M, Pankow JS, Blumenthal RS, Chen H, Keeler E. A graphical method for assessing risk factor threshold values using the generalized additive model: The Multi-Ethnic Study of Atherosclerosis. In press, Health Services and Outcomes Research Methodology. PMCID: PMC – Journal in Process

Negi SI, Pankow JS, Fernstrom K, Hoogeveen RC, Zhu N, Couper D, Schmidt MI, Duncan BB, Ballantyne CM. Racial differences in association of elevated interleukin -18 levels with type II diabetes – the Atherosclerosis Risk in Community (ARIC) Study. Diabetes Care. 2012; 35: 1513-1518. PMCID: PMC3379601

Billings LK, Hsu Y-H, Ackerman R, Dupuis J, Voight BF, ... Pankow JS, Karasik D, Meigs JB, Kiel DP, Florez JC. The impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes 2012; 61: 2176-2186. PMCID: PMC3402303

Haiman CA, Fesinmeyer MD, Spencer KL, Buzková P, Voruganti VS, ... Pankow JS. Consistent directions of effect for established type 2 diabetes risk variants across populations: The Population Architecture using Genomics and Epidemiology (PAGE) Consortium. Diabetes.  2012; 61: 1642-1647. PMCID: PMC3357304

Southerland JH, Moss K, Taylor GW, Beck JD, Pankow J, Gangula PR, Offenbacher S.  Periodontitis and diabetes associations with measures of atherosclerosis and CHD.  Atherosclerosis 2012; 222: 196-201.  PMCID: PMC – Journal in Process

Chow L, Li S, Eberly L, Seaquist E, Eckfeldt J, Hoogeveen R, Couper D, Steffen LM, Pankow JS. Estimated plasma Stearoyl Co-A dDesaturase-1 activity and risk of incident diabetes, The Atherosclerosis Risk in Communities (ARIC) Study. In press, Metabolism. PMCID: PMC – Journal in Process

Tokedo OA, Ellison RC, Pankow JS, North KE, Hunt SC, Kraja AT, Arnett DK, Djousse L. Chocolate consumption and prevalence of metabolic syndrome in the NHLBI Family Heart Study. In press, e-SPEN.

Tang W, Schwienbacher, Lopez LM, Ben-Shlomo Y, Oudot-Mellakh T, ... Pankow JS, et al. Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. American Journal of Human Genetics 2012; 91: 152-162. PMCID: PMC3397273

Professional Experience:

Professor, University of Minnesota, 2011-present

Division Training Committee Chair, 2012-present

Associate Professor, University of Minnesota, 2003-2011

Program Director, Epidemiology MPH Degree, 2007-2011

Assistant Professor, University of Minnesota, 2001-2003

Assistant Professor, University of North Carolina at Chapel Hill, 1997-2001

Honors:

Delta Omega Honorary Society in Public Health, 1997