Timothy R. Church, Ph.D.

Ph.D., Biometry, University of Minnesota, 1984

M.S., Biometry and Health Information Systems, University of Minnesota, 1979

B.A., Mathematics, Augustana College, 1974

Courses

PubH 8141, Doctoral Seminar on Observational Inference
PubH 6140, Occupational and Environmental Epidemiology

Spring 2010
6140: Occupational and Environmental Epidemiology

Research Interests:

Design, management, and analysis of clinical trials and environmental and occupational epidemiological studies, especially in the areas of screening for and prevention and etiology of cancer and cardiovascular disease; methods to incorporate model uncertainty into epidemiologic studies, mathematical representations of causal models, adjusting treatment effects for compliance in clinical trials, predictive probabilities for sudden cardiac death, and bias in observational studies of screening.

Recent Publications:

PEER-REVIEWED PUBLICATIONS (in press):

Sage SK, Gerberich SG, Ryan AD, Nachreiner NM, Church TR, Alexander BH, Mongin SJ. “School resources, resource allocation, and risk of physical assault against Minnesota educators.” Accident Analysis & Prevention.

Larson-Bright M, Gerberich SG, Masten AS, Alexander BH, Gurney JG, Church TR, Ryan AD, Renier CM. “Parents’ safety beliefs and childhood agricultural injury.” American Journal of Industrial Medicine 52(9).

Alexander BH, Lundin JI, Olsen GW, Church TR. “Ammonium perfluorooctanoate production and occupational mortality.” Epidemiology.

PEER-REVIEWED PUBLICATIONS:

Carlson KF, Gerberich SG, Alexander BH, Masten AS, Church TR, Shutske JM, Ryan AD, Renier CM. (2009) “Children’s behavioral traits and risk of injury: Analyses from a case-control study of agricultural households.” Journal of Safety Research 40(2): 97-103.

Croswell JM, Kramer BS, Kreimer AR, Prorok PC, Xu JL, Baker SG, Fagerstrom R, Riley TL, Clapp JD, Berg CD, Gohagan JK, Andriole GL, Chia D, Church TR, Crawford ED, Fouad MN, Gelmann EP, Lamerato L, Reding DJ, Schoen RE. (2009) "Cumulative incidence of false-positive results in repeated, multimodal cancer screening." Annals of Family Medicine 7(3): 212-22.

Andriole GL, Grubb RL 3rd, Buys SS, Chia D, Church TR, Fouad MN, Gelmann EP, Kvale PA, Reding DJ, Weissfeld JL, Yokochi LA, Crawford ED, O'Brien B, Clapp JD, Rathmell JM, Riley TL, Hayes RB, Kramer BS, Izmirlian G, Miller AB, Pinsky PF, Prorok PC, Gohagan JK, Berg CD; the PLCO Project Team. (2009) “Mortality results from a randomized prostate-cancer screening trial.” New England Journal of Medicine
360(13): 1310-9.

Partridge E, Kreimer AR, Greenlee RT, Williams C, Xu JL, Church TR, Kessel B, Johnson CC, Weissfeld JL, Isaacs C, Andriole GL, Ogden S, Ragard LR, Buys SS; for the PLCO Project Team. (2009) “Results from four rounds of ovarian cancer screening in a randomized trial.” Obstetrics and Gynecology 113(4): 775-82.

Grubb RL 3rd, Black A, Izmirlian G, Hickey TP, Pinsky PF, Mabie JE, Riley TL, Ragard LR, Prorok PC, Berg, CD, Crawford ED, Church TR, Andriole Jr GL, for the PLCO Project Team. (2009) “Serum prostate-specific antigen hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.” Cancer Epidemiology, Biomarkers and Prevention 18(3): 748-51.

Martinez ME, Baron JA, Lieberman DA, Schatzkin A, Lanza E, Winawer SJ, Zauber AG, Jiang R, Ahnen DJ, Bond JH, Church TR, Robertson DJ, Smith-Warner SA, Jacobs ET, Alberts DS, Greenberg ER. (2009) “A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy.” Gastroenterology 136(3): 832-41.

Pinsky PF, Schoen RE, Weissfeld JL, Church TR, Yokochi LA, Doria-Rose VP, Prorok P. (2009) “The yield of surveillance colonoscopy by adenoma history and time to examination.” Clinical Gastroenterology and Hepatology 7(1): 86-92.

Church TR, Anderson KA, Caporaso N, Geisser MS, Le C, Zhang Y, Benoit A, Carmella S, Hecht SS. (2009) “A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers.” Cancer Epidemiology, Biomarkers and Prevention 18(1): 260-6.

Grubb RL 3rd, Pinsky PF, Greenlee RT, Izmirlian G, Miller AB, Hickey TP, Riley TL, Mabie JE, Levin DL, Chia D, Kramer BS, Reding DJ, Church TR, Yokochi LA, Kvale PA, Weissfeld JL, Urban DA, Buys SS, Gelmann EP, Ragard LR, Crawford ED, Prorok PC, Gohagan JK, Berg CD, Andriole GL, for the PLCO Project Team. (2008) “Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: Update on findings from the initial four rounds of screening in a randomized trial.” BJU International 102(11): 1524-30.

Olsen GW, Mair DC, Church TR, Ellefson ME, Reagen WK, Boyd TM, Herron RM, Medhdizadekashi Z, Nobiletti JB, Rios JA, Butenhoff JL, Zobel LR. (2008) "Decline in perfluorooctanesulfonate and other polyfluoroalkyl chemicals in American Red Cross adult blood donors, 2000 – 2006.” Environmental Science & Technology 42(13):4989-95.

Jones RM, Mongin SJ, Lazovich D, Church TR, Yeazel MW. (2008) “Validity of four self- reported colorectal cancer screening modalities in a general population: Differences over time and by intervention assignment.” Cancer Epidemiology Biomarkers and Prevention 17(4): 777-84.

Gierada DS, Pilgram TK, Ford M, Fagerstrom RM Church TR, Nath H, Garg K, Strollo DC. (2008) “Lung Cancer: Interobserver agreement on interpretation of pulmonary findings at low-dose CT screening.” Radiology 246(1):265-72.

Larson-Bright M, Gerberich SG, Alexander BH, Gurney JG, Masten AS, Church TR, Ryan AD, Renier CM. (2007) “Work practices and childhood agricultural injury.” Injury Prevention 13(6): 409-15.

Tammemagi CM, Freedman MT, Church TR, Oken MM, Hocking WG, Kvale PA, Hu P, Riley TL, Ragard LR, Prorok PC, Berg CD. (2007) “Factors associated with human small aggressive non-small cell lung cancer.” Cancer Epidemiology, Biomarkers and Prevention 16(10):2082-9.

Nachreiner NM, Hansen HE, Okano A, Gerberich SG, Ryan AD, McGovern PM, Church TR, Watt GD. (2007) “Difference in work-related violence related to nurse license type.” Journal of Professional Nursing 23(5):290-300.

Jurek AM, Maldonado G, Greenland S, Church TR. (2007) “Uncertainty analysis: An example of its application to estimating survey proportion.” Journal of Epidemiology and Community Health 61(7): 650-654.

Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen G, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Robertson DJ, Beck GJ, Bond JH, Byers T, Mandel JS, Mott LA, Pearson LH, Barry EL, Rees JR, Marcon N, Saibil F, Ueland PM, Greenberg ER for the Polyp Prevention Group. (2007) “Folic acid for the prevention of colorectal adenomas - A randomized clinical trial.” Journal of the American Medical Association 297(21):2351-2359.

Bailey JJ, Hodges M, Church TR. (2007) “Decision to implant a cardioverter-defibrillator after myocardial infarction: The role of ejection fraction v. other risk factor markers.” Medical Decision Making 27(2):151-160.

Pinsky PF, Miller A, Kramer BS, Church T, Reding D, Prorok P, Gelmann E, Schoen RE, Buys S, Hayes RB, Berg CD. (2007) “Evidence of a healthy volunteer effect in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.” American Journal of Epidemiology165(8): 874-881.

Berndt SI, Huang W-Y, Fallin MD, Helzlsouer KJ, Platz EA, Weissfeld JL, Church TR, Welch R, Chanock SJ, Hayes RB. (2007) “Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma.” Cancer Research 67(3):1395-1404.

Grau MV, Baron JA, Sandler RS, Wallace K, Haile RW, Church TR, Beck GJ, Summers RW, Barry EL, Cole BF, Snover D, Rothstein R, Mandel JS. (2007) “Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial.” Journal of the National Cancer Institute 99(2):129-136.

Greaves IA, Sexton K, Blumenthal MN, Church TR, Adgate JL, Ramachandran G, Fredrickson AL, Ryan AD, Geisser MS. (2007) “Asthma, atopy, and lung function among racially diverse, poor inner-urban Minneapolis schoolchildren.” Environmental Research 103(1):257-266.

Jurek AM, Maldonado G, Greenland S, Church TR. (2006) “Exposure-measurement error is frequently ignored when interpreting epidemiologic study results.” European Journal of Epidemiology 21(12):871-876.

Kim S, Baron JA, Mott LA, Burke CA, Church TR, McKeown-Eyssen GE, Cole BF, Haile RW, Sandler RS. (2006) “Aspirin may be more effective in preventing colorectal adenomas in patients with higher BMI (United States). Cancer Causes and Control 17:1299-1304.

Flood AP, Peters U, Jenkins D, Chatterjee N, Subar AF, Church TR, Bresalier R, Weissfeld JL, Hayes RB, Schatzkin A, for the PLCO Project Team. (2006) “Carbohydrate, glycemic index, and glycemic load and colorectal adenomas in the Prostate, Lung, Colorectal, and Ovarian Screening Study.” American Journal of Clinical Nutrition 84(5):1184-1192.

Moslehi R, Chatterjee N, Church TR, Chen J, Yeager M, Weissfeld J, Hein DW, Hayes RB. (2006) “Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma.” Pharmacogenomics 7(6):819-829.

Peters U, Chatterjee N, Church TR, Mayo C, Stürup S, Foster CB, Schatzkin A, Hayes RB. (2006) “High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal early detection program.” Cancer Epidemiology, Biomarkers and Prevention 15(2): 315-320.

Professional Experience:

July 1980-July 1982 Biometrician, Biometry Group, Clinical Operations Department, Medtronic, Inc.
July 1982-Jan 1987 Manager of Biometry, Clinical Operations Department, Medtronic, Inc.
Jan 1987-May 1992 Research Assoc, Environmental & Occupational Health, University of Minnesota

May 1992-July 1996 Senior Research Assoc, Environmental & Occupational Health, University of Minnesota

Oct 1993-July 1996 Director, Tachyarrhythmia Clin Studies Ctr, Tachyarrhythmia Mgmt Business, Medtronic Inc.

July 1996-June 2005 Associate Professor, Division of Environmental Health Sciences, University of Minnesota

July 2005- present Professor, Division of Environmental Health Sciences, University of Minnesota

Contact

Mailing Address:
MMC 807, 1162 Mayo
420 Delaware Street Southeast
Minneapolis, MN 55455

Phone (Work): (612) 625-9091

Email: trc@cccs.umn.edu