Vaccines are a crucial tool for protecting individuals and communities against a wide range of infectious diseases. However, vaccine hesitancy, especially among marginalized communities, has been on the rise. This presentation will delve into historical and contemporary drivers of vaccine hesitancy among Black Minnesotans, highlighting issues specific to different communities in the State. Immunization data will be used to illustrate varying levels of immunization coverage among these communities, and how dips in vaccination rates put vulnerable Minnesotans at risk. Finally, potential solutions to this public health challenge will be discussed, with a focus on initiatives that center marginalized communities.