Cannabis is the most widely used drug after alcohol and tobacco. Over the past 20+ years the US and numerous other countries have been shifting from a prohibition model to regulated medical and adult use models. From a public health perspective cannabis is complex: it has both health benefits and risks, it is not addictive like tobacco or opiates, yet some develop persistent heavy use patterns, there are notable social equity concerns, and, while used by humans for centuries, good scientific evidence is scarce. This webinar will give a quick overview of cannabis, summarize levels and patterns of use, present what is currently known and not known about cannabis and health outcomes (including workplace outcomes), discuss the current regulatory environment and implications of those changes, and give a quick overview of the newly launched SPH Cannabis Research Center at UMN.